Many great changes have fallen upon the world these past few weeks. The most recent change was the changing of the seasons. Fittingly, Mega Millions saw a change in the Pattern line-up Friday night. This lottery welcomed fall (or spring for y’all south of the Equator) without a {2-1-1-1-1} Pattern encore. Nonetheless, the jackpot grew to an astounding $325 million.
General Lottery Analysis
September 23, 2022 belonged to the {2-2-1-1} Pattern. With winning numbers 5, 50, 53, 58, 64 and MB 22, this Pattern made its 224th appearance.

This Pattern has now played in 27.6% of the 813 Mega Millions drawings and was last seen September 9, 2022.
The [1-2-2-1] General Order, now with 77 appearances, has played in 34.375% of the 224 drawings where {2-2-1-1} was the winning Pattern. Once all 813 drawings have been taken into consideration, this General Order has played 9.47% of the time. The [1-2-2-1] General Order was last seen March 4, 2022.
Now with 10 appearances, the 1 0 0 2 2 1 Specific Order has played in 13% of the 77 drawings where the General Order was [1-2-2-1]. This Specific Order has also played in 4.46% of the 224 drawings where {2-2-1-1} was the winning Pattern and in 1.23% of the 813 drawings. Prior to Friday night, the 1 0 0 2 2 1 Specific Order played June 11, 2021.
Three-Number Combinations
Repeating Three-Number Combination 50, 53 and 64 debuted August 28, 2020.

Will the {2-2-1-1} Pattern take over Mega Millions in the final week of September?